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Published 2018 Jan 26

A 2021 analysis published in Cardiovascular Diabetology found that semaglutide produced significant reductions in triglycerides and total cholesterol alongside its weight loss effects, with improvements correlating strongly with the degree of weight lost (Husain et al., Cardiovascular Diabetology, 2021, Tirzepatide and Cholesterol: Does the Dual Mechanism Help More For patients with significant lipid abnormalities, tirzepatide may offer an advantage over semaglutide

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Glycemic control and type 2 diabetes: CagriSema has the more extensive diabetes-specific trial data (REIMAGINE program), with demonstrated superiority over semaglutide alone on both HbA1c reduction and weight loss in T2D populations

Rybelsus Rybelsus, another semaglutide drug made by Novo Nordisk, is an oral GLP-1 receptor agonist prescribed to treat type 2 diabetes